Mitochondrial matrix

TCA / Krebs cycle

Eight steps around, two carbons in, two CO₂ out.

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this pathway
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Net yieldPer turn: 3 NADH · 1 FADH₂ · 1 GTP · 2 CO₂
Rate-limitingIsocitrate dehydrogenase
Steps9
Irreversible4
Intermediates
Citrate Is Krebs' Starting Substrate For Making Oxaloacetate
Enzymes
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