Mitochondrial matrix
TCA / Krebs cycle mnemonics
Eight steps around, two carbons in, two CO₂ out.
Word by word
| Step | Word | Stands for | Enzyme word | Enzyme |
|---|---|---|---|---|
| · | Acetyl-CoA | (entry) | Pyruvate dehydrogenase complex | |
| 1 | Citrate | Citrate | Citrate synthase | |
| 2 | Is | Isocitrate | Aconitase | |
| 3 | Krebs | α-Ketoglutarate | Isocitrate dehydrogenase | |
| 4 | Starting | Succinyl-CoA | α-Ketoglutarate dehydrogenase | |
| 5 | Substrate | Succinate | Succinyl-CoA synthetase | |
| 6 | For | Fumarate | Succinate dehydrogenase | |
| 7 | Making | Malate | Fumarase | |
| 8 | Oxaloacetate | Oxaloacetate | Malate dehydrogenase |
A mnemonic only sticks once you have used it. The quiz and the rebuild below both draw on these exact steps.