Mitochondrial matrix
TCA / Krebs cycle mnemonics
Eight steps around, two carbons in, two CO₂ out.
Word by word
| Step | Word | Stands for | Enzyme word | Enzyme |
|---|---|---|---|---|
| · | Acetyl-CoA | (entry) | Pyruvate dehydrogenase complex | |
| 1 | Citrate | Citrate | Captain | Citrate synthase |
| 2 | Is | Isocitrate | America's | Aconitase |
| 3 | Krebs | α-Ketoglutarate | Irate | Isocitrate dehydrogenase |
| 4 | Starting | Succinyl-CoA | Avengers | α-Ketoglutarate dehydrogenase |
| 5 | Substrate | Succinate | Spoke | Succinyl-CoA synthetase |
| 6 | For | Fumarate | Slander | Succinate dehydrogenase |
| 7 | Making | Malate | For | Fumarase |
| 8 | Oxaloacetate | Oxaloacetate | Money | Malate dehydrogenase |
A mnemonic only sticks once you have used it. The quiz and the rebuild below both draw on these exact steps.