Liver: mitochondria, then cytosol

Urea cycle

Two nitrogens in, one urea out.

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this pathway
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Net yieldCosts 3 ATP (4 high-energy bonds) per urea
Rate-limitingCarbamoyl phosphate synthetase I
Steps5
Irreversible5
Cycle order
Ordinarily Careless Crappers Are Also Frivolous About Urination